3D Printed Pill Allows Tailored Dosage

spritam

A 3D printed pill has become the first such drug to get Food and Drug Administration approval. The benefits include the ability to precisely control dosage.

The drug from Aprecia has the brand name SPRITAM and is a form of levetiracetam. It’s primarily designed as a way to control seizures in people with epilepsy.

While the printing material is the drug itself rather than a polymer such as a plastic, the basic principle of the 3D printing is the same as usual. One of the big keys to the drug is that using the 3D printer makes it much more viable to produce a pill with a specific dosage for a specific patient.

That’s in contrast to normal mass drug production where it’s usually only economic to produce a limited range of sizes. Moving away from mass production could also mean drugs could be produced nearer to patients, cutting shipping costs and times.

The other advantage of the 3D printing process, known as ZipDose, is that the printed pill can be structured to make it particularly porous. In turn, that means it can dissolve almost instantly even with only a small sip of liquid. That’s particularly useful with levetiracetam where some prescribed doses can be up to a full gram, an amount that can be uncomfortable for some patients to swallow in a traditionally-manufactured drug.

Aprecia plans to adapt the technique to work with other drugs.


Fantastic Portal Fan Film: Portal Combat [Video]

A fantastic Portal-inspired fan film made by the folks over at Film Riot.

[Film Riot]

The folks over at HitFilms make some pretty awesome low-budget videos showcasing some rather impressive VFX knowledge. This one from earlier this month was a funny video spoofing Valve’s popular Portal series called “Portal Combat.” I’ve seen a lot of Portal inspired videos on YouTube, but this one has some pretty fun humor to it, not just cool Portal trick gags. It was written and directed by Ryan Connolly, and it’s worth a watch. I definitely recommend subscribing to HitFilms.

Make An Iron Man Arc Reactor at Home For Just $30! [Video]

We build so many amazing weapons and props, we wanted to offer a show where you at home could build them yourself! Follow along with our host Dustin McLean (“Homemade Movies”) as he shows you how to build awesome props from all of your favorite movies & games, for under $50! This week, channel your inner Tony Stark and learn how to build an Arc Reactor. Save The World!

[AWE me]

How to Activate “God Mode” in Windows 10

god1

The feature first appeared in Windows 7, but in case you were not aware of it, “God Mode,” which is a hidden menu allowing you to access all available configuration parameters in one simple location, is still available in Windows 10.

The only thing your need to do to activate “God Mode” is to create a new folder on you desktop (right click your desktop -> New -> Folder) and then assign this name to it: GodMode.{ED7BA470-8E54-465E-825C-99712043E01C}

That’s all you need to do! The folder should look like this:

godmode

And here’s what you’ll find in it:

Click Picture to Enlarge!

Click Picture to Enlarge!

As you can see, accessing all these important parameters is now just a click away!

Have fun!

Thanks Korben!