Here’s a short video in which David Bradley, the original inventor of Ctrl + Alt + Del, explains why this particular combination of keys came into existence. He then goes on about how someone we all know very well helped popularize the command.
This keyboard combination was implemented by David Bradley, a designer of the original IBM PC. Bradley originally designed Control-Alt-Escape to trigger a soft reboot, but he found it was too easy to bump the left side of the keyboard and reboot the computer accidentally. He switched the key combination to Control-Alt-Delete, a combination impossible to press with just one hand. (Source: Wikipedia)